TERATOLOGY

Vragen, informatie en discussie over zwangerschap en de ziekte van Lyme.
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vonneke
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Lid geworden op: Do 16 Jun 2005 20:57

TERATOLOGY

Berichtdoor vonneke » Vr 18 Apr 2008 10:54

Teratologie= wetenschap van de aangeboren afwijkingen

Teratogen Update: Lyme Disease

ABSTRACT We reviewed the world literature
concerning the reproductive effects of Lyme disease
(LD). Borrelia burgdorferi, which is the etiology of LD, is
a spirochete and, as such, may share the potential for
causing fetal infection, which may occur in the setting
of maternal spirochetemia. Information concerning the
effects of gestational LD derives from case reports
and series, epidemiologic studies, and experimental
animal models. Although provocative, these studies fail
to define a characteristic teratogenic effect. However,
skin and cardiac involvement have predominated in
some reports. Pregnancy wastage has been suggested
primarily by animal studies. Gestational LD appears
to be associated with a low risk of adverse
pregnancy outcome, particularly with appropriated antibiotic
therapy. Suggestions for management of clinical
situations are presented. Teratology 64:276–281,
2001. © 2001 Wiley-Liss, Inc.


http://www.teratology.org/updates/64pg276.pdf

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