Psychiatrische problemen bij lyme

Wetenschappelijke onderwerpen die betrekking hebben op de ziekte van Lyme, zoals wetenschappelijke medische publicaties en artikelen die worden ondersteund door dergelijke publicaties.
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vonneke
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Psychiatrische problemen bij lyme

Berichtdoor vonneke » Di 19 Sep 2006 15:42

Mental illnesses associated with these frequently unsuspected infections include, but are not limited to, depression, phobias, obsessive-compulsive disorders, panic disorders, aggressiveness, delusions, irritability, suicidality, exhaustion, sexual dysfunction, sleep disorders, eating disorders, and a broad spectrum of cognitive and neurological impairments. Findings more common in children include autism, Tourette syndrome, attention deficit disorder, dyslexia, lethargy, and a decline in grades, tantrums;

http://www.psych.org/pnews/98-09-18/lyme.html

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vonneke
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Berichtdoor vonneke » Do 21 Sep 2006 12:15

Lyme borreliosis (Lyme disease) is a multisystem illness caused by the spirochete Borrelia burgdorferi. Although dermatologic, articular, cardiac, opthalmologic, and neurologic manifestations are well known, it is less well known that psychiatric disorders may also arise as a result of borrelial infection (1). Depression (2), panic attacks (3), schizophrenia-like psychotic state (4), bipolar disorder (3), and dementia (5) have been atributed to Lyme borreliosis. In this report, we present two patients in whom psychiatric symptoms represented the primary manifestations of their late-stage Lyme borreliosis. Specific dilemmas of diagnosis and treatment will be discussed.

http://www.wadhurst.demon.co.uk/lyme/lyme101.htm

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vonneke
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Berichtdoor vonneke » Zo 24 Sep 2006 8:06

The emotional and behavioral symptoms caused by Lyme disease are more complex to understand than the cognitive impairments. Let’s first review the physiology of emotion. The different emotional functions have a hierarchy of circuitry, which includes stimulatory pathways, opposing inhibitory pathways, and a hierarchy of modulation centers. The basic hierarchy is pre-frontal cortex, para limbic association areas, limbic structures, and brain stems - hypothalamus. Lyme encephalopathy can result in dysfunction of the modulation centers, inhibitory pathways, and stimulatory pathways. Autopsies, animal studies, and brain imaging tests have contributed to this understanding. The presenting symptoms of NPLD are sometimes emotional in nature, and include obsessive-compulsive disorder, depression, and aggression, panic disorder, and other phobic disorders.

In considering the behavioral symptoms, these patients can become suddenly suicidal and there have been completed suicides attributed to Lyme disease. Homicidal ideation, urges, and behavior occur in some of these patients. Some adult patients describe struggling to not act on these urges. When these patients act on a homicidal urge, more commonly it is a child becoming assaultive to a sibling. Dissociative episodes sometimes occur with these patients occasionally accompanied with aggressive behavior and loss of memory.

Compensatory compulsions are common in an effort to compensate for the memory deficits. NPLD can imitate a number of common psychiatric syndromes. It can be difficult to differentiate Lyme disease from rapid cycling Bipolar illness or Posttraumatic Stress Disorder. Eating disorders are common. Invariably these patients either gain or lose weight. Sometimes massive weight gain is also seen.

http://www.geocities.com/playpub/AR-NB-Bransfield.htm#_Toc117140320

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vonneke
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Berichtdoor vonneke » Zo 24 Sep 2006 8:15

I would estimate aggressive behavior has been a significant issue for approximately fifty patients with LD that I have evaluated or treated, although many more have reported some symptoms associated with aggressive potential. When aggression does occur, it may only be present for an interval in the progression of the illness.

Deficits caused by LD that are sometimes associated with increased risk for aggressive behavior may include:

1. Decreased frustration tolerance. (This is magnified by the increased frustration caused by a chronic illness).

2. Decreased impulse control.

3. When mild, the combination of decreased frustration tolerance and decreased impulse control leads to irritability. When more extreme, this combination can result in explosive anger.

4. Hyposexuality and hypersexuality caused by LD, both of which cause increased interpersonal frustration.

5. Dysfunction causing different forms of obsessive compulsive disorder, which results in intrusive thoughts, images, and compulsions that sometimes are of an aggressive nature.

6. Some dysfunction results in a decreased bonding capacity.

7. Increased startle reflex - particularly increased acoustic startle.

8. Hyper vigilance and paranoia

9. Delusions and hallucinations.

10. Some patients acquire impairment in their ability to regulate the arousal level of an emotion. As a result, emotions such as anger may be all or none, excessively intense, and not proportionate to the current situation. This also leads to a decline in the ability to integrate concurrent emotions that exist either within the patient or in a relationship with another person. This symptom may in turn intensify other psychiatric syndromes such as post-traumatic stress disorder, dissociative disorders, borderline personality, and narcissistic personality disorders.


http://www.geocities.com/playpub/AR-NB-Bransfield.htm#_Toc117140319

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vonneke
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Psychiatrische symptomen als Herxreactie

Berichtdoor vonneke » Zo 24 Sep 2006 8:24

Worsening of Symptoms During Antibiotic Treatment

Nearly half of the patients in our sample reported a transient worsening of neuropsychiatric symptoms during the first few days of antibiotic treatment. The worsening of symptoms during initiation of antibiotic treatment is thought to be a variant of the Herxheimer reaction as seen in the treatment of syphilis (33). In Lyme disease, however, this Herxheimer-like reaction can be quite prolonged-lasting a few days or longer-and can be frightening to patients who are expecting a resolution, not a worsening, of their symptoms. The reaction can sometimes be difficult to distinguish from an allergic reaction to the medicine, a distinction with obvious and crucial treatment implications.

This Herxheimer-like reaction may be experienced as a worsening of psychiatric symptoms: some patients in our sample experienced panic attacks for the first and only time when starting on antibiotics. Others have reported an intensification of depressive symptoms, suicidality or anxiety. Many reported an increased startle response and photophobia during the first few days of antibiotic treatment.



http://www.geocities.com/playpub/AR-NB-Fallon.htm#_Toc119817522

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vonneke
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Meer borrelia antistoffen bij psychiatrische patienten

Berichtdoor vonneke » Wo 4 Okt 2006 19:35

Higher Prevalence of Antibodies to Borrelia Burgdorferi in Psychiatric Patients Than in Healthy Subjects
Tomá Hájek, M.D., Beáta Paková, M.D., Daniela Janovská, M.D., Radvan Bahbouh, M.D., Peter Hájek, Ph.D., Jan Libiger, M.D. and Cyril Höschl, M.D., M.R.C.Psych.
OBJECTIVE: Borrelia burgdorferi infection can affect the CNS and mimic psychiatric disorders. It is not known whether Borrelia burgdorferi contributes to overall psychiatric morbidity. The authors compared the prevalence of antibodies to Borrelia burgdorferi in groups of psychiatric patients and healthy subjects to find out whether there is an association between this infection and psychiatric morbidity. METHOD: Between 1995 and 1999 the authors screened for antibodies to Borrelia burgdorferi in 926 psychiatric patients consecutively admitted to Prague Psychiatric Center. They compared the results of this screening with findings from 884 consecutive healthy subjects who took part in an epidemiological survey of antibodies to Borrelia burgdorferi in the general population of the Czech Republic. Sera were tested by means of enzyme-linked immunosorbent assay. Circulating immune complexes were isolated by polyethylene glycol precipitation. To control for potential confounders, the two groups of patients and healthy subjects were matched according to gender and age. Results were obtained in a sample of 499 matched pairs. RESULTS: Among the matched pairs, 166 (33%) of the psychiatric patients and 94 (19%) of the healthy comparison subjects were seropositive in at least one of the four assays. CONCLUSIONS: These findings support the hypothesis that there is an association between Borrelia burgdorferi infection and psychiatric morbidity. In countries where this infection is endemic, a proportion of psychiatric inpatients may be suffering from neuropathogenic effects of Borrelia burgdorferi.



http://tinyurl.com/qybts

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vonneke
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Berichtdoor vonneke » Wo 4 Okt 2006 19:55

Psychiatric Aspects in Adults
Irritability and moodiness are common. These tend to be most severe in neurologic Lyme disease before treatment, during the first few days or weeks of treatment, and during resurgences or relapses of active Lyme Disease. Antibiotic therapy can be very helpful at these times. Symptoms that persist despite appropriate antibiotic therapy should be treated with psychiatric medications. It is very important for patients to take advantage of all opportunities for therapeutic benefit. These include consultation with a psychiatrist for both medication and therapy. Psychotherapy with a psychiatrist, psychologist, or social worker can be very helpful to help the individual cope with the effects of a serious illness. Family and couples therapy can also be vitally important, particularly when family members are confused by the changed behavior or personality of the patient. Psychiatric medication can be very helpful to combat mood and sleep disturbances, to enhance attention, to decrease central nervous system hyperacuities, to decrease excessive worry and fear, and to contribute to overall good health by countering the negative impact of neuropsychiatric disorders on the immune system.

Mood Lability: spontaneous swings of mood; spontaneous tearfulness. At times, patients with these symptoms may appear to have a Bipolar II disorder.
Irritability: an inability to tolerate normal frustrations, with quick bursts of anger. Patients may seem to have undergone a personality change in that previously mild-mannered individuals may now become quite difficult.
Panic attacks: tachycardia, flushing, chest pain, , numbness and tingling, shortness of breath, choking feeling with the sensation of loss of control and/or of fear of death. Needs to be distinguished from tachyarrhythmias. Panic attacks unrelated to Lyme disease are usually 10-20 minutes in duration. Lyme-related panic attacks may last for an hour or more.
Less commonly: manic or psychotic episodes (during encephalitic phase), paranoia, tics, obsessive/compulsive symptoms (may trigger a milder pre- existing condition or bring on symptoms de novo)

http://www.columbia-lyme.org/flatp/lymeoverview.html#adult-psych

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vonneke
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Berichtdoor vonneke » Zo 8 Okt 2006 9:52

Zeckenkrankheiten und Neuropsychiatrie

EINLEITUNG
Als ich 1976 von meiner oberärztlichen Tätigkeit an der Universität in die eigene Praxis
wechselte, da wussten wir noch nichts von Lyme-Borreliose und also auch nichts über
deren Zusammenhänge mit psychiatrischen Krankheitsbildern. In meiner Praxis sah
ich dann immer wieder Patienten, die erstaunlich schlecht auf sonst meist erfolgreiche
Therapien ansprachen. Sie waren gekommen wegen chronischen, teils
allerschwersten Depressionen, Angstzuständen oder Panikattacken.

2. Antriebs - Störungen, insbesondere
chronische Müdigkeit und Apathie (Antriebsschwäche) oder
zeitweilige Agitiertheit (abnormale Angetriebenheit)

3. Vigilanz - Störungen, insbesondere
häufige Benommenheit, Dösigkeit und
Überwachheit (Hypervigilanz)

4. Störungen von Schlafqualität und Schlafperiodik
Insomnie (Schlaflosigkeit),
Hypersomnie (abnormales Schlafbedürfnis) oder
Schlaf-wach-Umkehr

5. kognitive Störungen, insbesondere, wenn diese immer häufiger werden
oder in Schüben auftreten, also
Denkstörungen, z.B. Verwirrtheit, Perseverationen,
Konzentrations- oder Leseschwierigkeiten
Gedächtnisstörungen, z.B. Vergesslichkeit
Wortfindungsstörungen und Wortverwechslungen
Sprech- oder Schreibschwierigkeiten
Wahrnehmungs- Störungen z. B. auch rasches überflutet Werden
mit Sinneseindrücken (optisch, akustisch) oder „brain fog“
Störungen der räumlichen Orientierung im Nahbereich (anstossen,
danebenlangen) und weiteren Bereich (wo habe ich nun schon
mein Auto parkiert?)
Verminderung des Abstraktiosvermögens
zunehmende Rigidität (übertriebenes Festhalten an
Überzeugungen)

6. affektive Störungen sei es qualitativ oder quantitativ, insbesondere
hartnäckige oder therapieresistente Depressionen
Angstsyndrome, Phobien und Panikattacken
unangemessene Verstimmungen, Gereiztheit und Wutausbrüche
oder Stimmungslabilität

7. Störungen im vegetativen und im instinktiven Bereich
Temperatur-Auffälligkeiten mit leichten Fiebern oder
Untertemperatur
Nachtschweisse
Libidoverlust oder sexuelle Getriebenheit
Dranghaftes oder einschiessend zwanghaftes Denken oder
Handeln, z.B. dranghaftes oder impulsives Essen, Lachen,
Weinen, Fluchen, Weglaufen , etc
Physische oder psychische Überreaktion auf gängige Noxen wie
Alkohol, Koffein Nikotin bis zur völligen Unverträglichkeit
Physische oder psychische Überreaktion oder paradoxe Reaktion
auf Psychopharmaka (oft auf kleinste Mengen)

8. Als psychotisch imponierende Störungen
Zustände mit Wahn, Halluzinationen etc (= meist komplexe
Mischungen aus Störungen Typ 1-6)

9. Schmerzangaben und Sensibilitätsstörungen, welche als „psychogen“
imponieren können, weil sie schlecht in ein neurologisch zuordenbares
Verteilungsmuster passen. Besonders häufig sind quälende
Kopfschmerzen- und Gesichts-Schmerzen, Gelenkschmerzen mit oder
ohne Entzündungszeichen, Muskelschmerzen und heftige, stechende
oder brennende oder bohrende Schmerzen an den verschiedensten
Körperpartien, sowie - als Zeichen peripherer Neuropathie -
Gefühlsstörungen oder Ameisenlaufen an Händen oder Füssen.

10. Auffälligkeiten in den psychosozialen Wechselwirkungen
parallel zum Fortschreiten einer psychischen Störung durch
Zeckenerkrankung steigt gezwungenermassen auch das Risiko, mit der
Umgebung in verhängnisvolle Verstrickungen zu geraten.

Achtung: Psychische Auffälligkeiten können über Monate die einzige
Manifestation eines Mischinfektes nach Zeckenbiss sein!

http://www.zeckenliga.ch/downloads/vortragkasselwvlversion10.03.2004.pdf

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ogee Open
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Lid geworden op: Do 20 Jul 2006 19:00

Berichtdoor ogee Open » Zo 8 Okt 2006 14:26

Vonneke


Allemaal mentale verschijnselen die deze LICHAMELIJKE kwaal met zich meebrengt. Niet andersom. Als je de LICHAMELIJKE verschijnselen behandel, verdwijnen die mentale en geestelijke verschijnselen vanzelf.

Ga je die mentale en geestelijke verschijnselen behandelen dan verdwijnt die lichamelijk kwaal NIET.

Wel loop je vaak onherstelbare schade op als je met medicatie die verschijnselen probeer te pakken.

Ogee

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vonneke
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Berichtdoor vonneke » Zo 8 Okt 2006 15:29

Hoi Ogee

Ja, waarom dacht je anders dat ik dit hier post ?
En de artsen dit in bovenstaande artikelen naar buiten brengen ?

Ze schrijven ook dat dit soort symptomen te zien zijn voor de behandeling, en de eerste dagen of weken van behandeling met AB en tijdens heropleving en bij terugval. En dat AB hierin zou kunnen helpen en dat bijdiegenen bij wie de symptomen ondanks AB toch nog blijven bestaan daarnaast psychiatrische medicijnen soms wenselijk zijn.

Groetjes, Yvonne

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