Understanding Lyme tests

Voor allerlei onderwerpen met vragen, informatie en discussie dat betrekking heeft op de ziekte van Lyme, maar dat niet bij de secties "Wetenschap" en "Medisch" past. Dus geen medische vragen.
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Lid geworden op: Di 19 Apr 2011 19:52

Understanding Lyme tests

Berichtdoor Tulipano » Zo 2 Feb 2014 22:26

Bron: Understanding Lymedisease

Bron: MDJunction, 19 september 2013
http://www.mdjunction.com/forums/lyme-d ... ts-ongoing


The committee proposed limiting the bands that could be reported in a Western Blot for diagnosis of Lyme disease. Out of a possible 25 bands, 10 specific bands were selected as being reportable.

An lgG Western Blot must have five or more of these bands: 18, 21,28, 30, 39, 41,45, 58, 66 and 93 kDa.
An lgM Western Blot must have two or more of the following three bands: 23, 39, 41.

Conspicuously absent are the most important bands, 22, 23, 25, 31, and 34, which include OSPA, OSP-B and OSP-C antigens – the three most widely accepted and recognized Bb antigens.

These antigens were the antigens chosen for human vaccine trials. In *Betina Wilska’s clinical experience (*German M.D.), if a patient has symptoms suspicious for borreliosis, and has one or more of the following bands, there is a very high probability the patient has borreliosis.

These bands are 18, 22, 23-25, 28, 30, 31, 34, 37, 39, 41, 83, and 93.

This is true regardless of whether it is IgG or IgM. However there is no universal agreement on the significance of these bands.

Many of the people who were vaccinated against Lyme were testing positive afterwards on certain bands of the Western Blot. Because of this, the IDSA decided to remove certain bands from the Western Blot, even though they were Lyme specific. Many believe that is one reason the Western Blot gives many false negatives now.

Voor de interpretatie van de CD57 waarden:

Let op:

There have been instances where high amounts of CD57 natural killers cells have been found in those with Chronic Lyme Disease and and low amounts of CD57 natural killer cells in those who were believed to be in remission. This is why the CD57 Test is not clinically reliable for diagnosing Lyme Disease.

•High CD57 levels with symptoms could be an indication that one is actually dealing with a co-infection, as opposed to Lyme itself.

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